It is an obesity hormone or an oily hormone, but also known as the hunger hormone. When scientists discovered leptin in 1994, they were delighted with the possibility of using it as a treatment for weight loss. Even today, there are websites on the Internet that sell leptin supplements. Is there any truth in these areas? And what is leptin?
About Leptin?
Leptin is a protein formed in fat cells that circulates in the blood and enters the brain. Leptin is when your fat cells tell your brain that the energy thermostat is properly set. Leptin tells your brain that enough energy has accumulated in your fat cells to engage in normal and relatively expensive metabolic processes.
In other words, if the Leptin xi hormone type is within a certain limit for everyone, it is likely that when your leptin level is higher than this level, it is genetically determined, the brain feels that you have enough energy, that is, you are burning energy at a normal possible level. it is possible to eat a normal amount, exercise at a normal level, and engage in inexpensive processes such as puberty and pregnancy.
How Does Leptin Affect Weight
If this thing works like a fat control thermostat, why keep gaining weight now? The problem is that overweight people have high levels of leptin, but their brains don't have a strong signal to stop eating.
How can the brain not accept it? This phenomenon is called "leptin resistance", which has been the subject of research on the subject. Resistance to leptin is similar to resistance to insulin in type 2 diabetes, in which the pancreas produces large amounts of insulin, but the body does not respond adequately. Leptin levels can increase with human fat. We all have a leptin floor, the problem is that we don't have a leptin ceiling.
Leptin Resistance
The amount of leptin in leptin resistance is high, which means that you are obese, but your brain cannot see it. In other words, when your brain is hungry, your body is obese. And this is obesity: it is cerebral famine. Not only is the leptin part of the starvation system, but it is also part of the reward system. When the amount of leptin is low, the food becomes more nutritious. If your leptin content is high, you should turn off the reward system to avoid consuming too much food, and the food will certainly not be good.
But in people who are resistant to leptin, the reward system does not force a person to stop eating when leptin levels rise. Leptin is produced by fat cells, brain fat cells Hey, I don't have to eat a lot, but the brain can't report. You're hungry and the reward doesn't go away. It's just fed and so right now. because you eat more and keep going and it becomes a sad cycle. If your brain does not see the leptin signal, you will gain weight.
Can Leptin Work As An Obesity Treatment?
Many scientists have studied leptin as a treatable way to treat obesity, believing that giving people leptin when they are deficient increases the level that gives them a signal to stop overeating. But when you started giving it to people, it didn't work so well. This thing is created by the fatty tissue and when you press the fat, you do more than that. It was very surprising because all obese people thought they were deficient in leptin.