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Living With HIV - What are the most promising treatments in development for HIV?

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What are the most promising treatments in development for HIV advice? You have to read this until the end because I have included everything I know about current research about finding HIV complete cure? when we talk about HIV, the most important question is there is a cure for HIV will be found anyone who is even having the suspicion or just a baseless doubt of having the deadly infection thinks his life is hell and over then he starts visualizing his death straightway this despite having modern treatment procedures such as arts.

Since the 1980svarious antiviral drugs have come into play to decrease the nuisance of HIV in the human body and to control the disease progress which has combined with alternative medical therapies, healthy diet, good hygiene, and a positive mental attitude make it manageable to such an extent that one can lead an anal most normal life with a life expectancy of 10 to 15 years longer than in the 1980s. In reality, HIV infection is no more deadly disease has made it a chronic disease that is treatable but cannot be cured, but still, all these are treatments only, and none promises a cure. Scientists worldwide are working on it sooner or later.

It will be found the only mystery is when recently some new approaches are being investigated, and some light is emerging which may lead to the cure of HIV infection. Examples include a first-in-class medicine intended to prevent HIV from breaking through the cell membrane. This cell therapy modifies a patient's cells in an attempt to make them resistant to HIV . a therapeutic vaccine designed to induce responses from t cells that play a role in immune protection against viral infections below is a quick look at some of the most promising strategies that researchers believe will one day lead to a cure for the disease which has killed more than 30 million people to date one therapeutic vaccine.

Unlike normal vaccines designed to prevent infection, therapeutic vaccines would treat infected people by boosting their immune systems enough to combat the virus itself. About one in 300 people infected with HIV have the natural ability to keep the HIV in check without antiretroviral treatment researchers have studied many of these so-called elite controllers to figure out how to translate this to normal immune systems. The goal is containment, not eradication, thus providing what is known as a functional cure because of a rare genetic mutation. An estimated one percent of people of northern European descent are virtually immune to HIV. Their t cells lack a particular receptor called ccr5which HIV requires to bind to and infect the cell.

These are the type of cells that were successfully transplanted into timothy ray brown, the so-called Berlin patient making him the first man to be functionally cured of the disease scientists are hoping to simulate the cellular immunity by turning off theccr5 receptors of those with HIV giving the disease nothing to latch onto like a therapeutic vaccine. This type of cure would not eradicate every last bit of HIV in the body, but it could deprive the virus of a place to dock, negating the need for arms and rendering the patient non-infectious.

Another variety of receptors known ascxcr4 is also present in t cells like the ccr5 receptor. It is also important in the binding of HIV three sterilizing cures despite locating hidden HIV reservoirs. Some researchers have not given up hope of completely eradicating the virus in the body. So-called sterilizing cures would first seek to contain the virus as treatment. Still, as scientists are well aware, HIV continues to hide in resting memory t cells. Having integrated its viral DNA into the cell's DNA, antiretroviral drugs blocked the virus from infecting new cells.

So if the reservoir of these memory cells could be eliminated, the HIV would theoretically have nowhere left to hide the problem is these infected t cells are indistinguishable from uninfected ones. so researchers are looking for ways to activate the HIV selectively

virus in these infected cells, thereby causing the cell to rupture and die however this method might prove more complicated if researchers find other reservoirs in the body which could require different means of activation for killing off HIV at the genetic level for patients who have already contracted the virus.


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Living With HIV - What are the most promising treatments in development for HIV?

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Updated on June 23, 2021

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